Stem Cell Testimonial for Knee Pain

Knees are the most common joint we see in the clinic for those interested in regenerative cell therapy. Check out Peggy discussing her experience with her stem cell injection at Governor’s MedSpa & Concierge Medicine.

If you are located in the Atlanta area and you are wondering if you may be a candidate for this procedure give us a call to schedule a free consult by calling (678) 888-5181. We will sit down with you to learn more about your case and see if stem cell therapy may be right for you.

Call (678)888-5181 to schedule an imaging review.

What is Regenerative Medicine?

Regenerative medicine is the future of how we treat conditions and disease. Regenerative medicine is the newest branch of medicine which uses biologics to treat conditions and diseases. It’s called regenerative medicine because the goal is to heal and regenerate damage, injured and/or arthritic tissue. The practice of regeneration is done at medical clinics which employ traditional nurse practitioners or medical doctors.

Medicine especially for joints will never be the same since regenerative medicine has been introduced. Previously, those suffering from joint pain, bursitis, tendinitis were getting harmful cortisone injections to rid of inflammation and repeating up to 3-4x’s/year (the FDA cap). You know it is not good for you when the FDA puts a cap on the number of injections you can receive per year. Research suggests that tendons may rupture, cartilage can deteriorate and other complications may occur from receiving just one cortisone injection.

Regenerative medicine involves biologics that innately heal the body without being synthetically altered in a lab preventing it from being a pharmaceutical drug.  There are a few choices when it comes to determining which regenerative therapy may be right for you. 

In our clinic, the team meets to determine the best intervention for the individual. Our protocols are unique. We have developed a system of delivery and instruction which gives the patient a better chance at repairing the joint(s). We often give pre and post injection instructions, perform follow-ups, incorporate some form of physical medicine (like chiropractic or physical therapy), weight loss, BioTE, supplements or other.

We really do curtail our care to the individual. If you are a local patient we may incorporate more physical medicine in your protocol than someone who travels from a nearby state. However, we might make a recommendation for an out-of-towner to find a specific healthcare provider. We often help to find the right type of provider that will be a great fit for you.

Within regenerative medicine there are a few different modalities which are listed below. Joint pain, swelling, ligament tears, tendinitis, bursitis issues do well with stem cell therapy. There are other options, but stem cell therapy is typically the gold standard in regenerative medicine.

  1. Stem cell therapy
  2. Platelet-rich Plasma (PRP)
  3. Prolotherapy
  4. Ozone injections

Each of the above regenerative options will be explored in future posts.

Painful joints due to injury or wear and tear arthritis.

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What does it mean to truly be healthy?

Health is not purely the absence of disease, but it is the full expression of you chemically, physically and emotionally. Everyday we are faced with thousands of decisions we make consciously and unconsciously which will affect our health.

The thoughts we think, the food we eat, the air we breath, the water we drink, the stress we accumulate, the sleep we get, the exercise we do or don’t do, etc… These are all building decision that have created our current state of health. You may feel tired, stressed, worn out, overwhelmed, fat, lazy, etc due to how you handle some of these daily health decisions.

I’m going to tell you it’s still okay. It took you years to earn the body and health you have now. Over 90% of all health conditions are self-induced meaning we did it to ourselves. You got to where you are over the course of years. Don’t fret, a diagnosis or condition is not a death sentence. Most of our chronic diseases that plague this country, costing billions of dollars, are often self-inflicted. It definitely easier to avoid a disease/conditions than it is to fix it.

I personally fell victim to these stresses which led me to poor diet, nicotine dependence and self pity. I let these things define me after my stress burden overwhelmed me and I didn’t know what to do. Rather than make good health decisions I beat myself up physically, chemically and emotionally.

But I’m here and I overcame it. You will too! I look forward to hearing more stories from you guys. Until then, keep on keeping’ on, but in a healthy manner…

Stem Cell FAQ

This page is for answering some of the most common questions.

What are stem cells?
Stem cells are the basic building blocks of human tissue. They have the ability to repair, rebuild and rejuvenate tissues throughout the body. When disease or injury strikes, stem cells respond to specific signals and set out to facilitate the healing process by differentiating into specialized cells. These specialized cells then release healing growth factors in response to the distress cell signal in an injured or pathologic area of the body required for the body’s repair.

Where do the stem cells come from?
The human cell and tissue products are derived from the umbilical cords of healthy, full-term deliveries. Our products do not contain any embryonic or fetal tissue.W

How are the tissue donors screened?
Comprehensive medical and social histories of the donors are obtained and reviewed. All tissues are procured, processed and tested in accordance with FDA requirements to minimize potential risks of disease transmission to recipients. Infectious disease testing is performed at a registered laboratory in accordance with the Clinical Laboratory Improvement Amendments of 1988 (CLIA) and 42 CFR part 493.

How long does a procedure take?
Depending upon the area being treated, the procedure can be completed in a single office visit. Your physician will be able to provide details specific to your treatment plan.

Does my age matter?
Your age may play a factor in the outcome of your treatment. We will be able to provide you with more specific information in regard to your treatment outcomes.

Does the procedure hurt?
The injection does not require any invasive procedures, resulting in less pain and a shorter procedure time.

When will I begin to feel the benefits?
Depending upon the severity of the injury and your personal health, recovery time can vary. Your physician will be able to provide you with more information regarding your recovery timeline.

Is it safe?
Our products are rigorously tested to FDA guidelines in our CLIA registered lab. Thousands of patients have used these tissue allografts with no adverse effects.

Can I use if I have cancer?
Human cell and tissue products are not recommended for use in patients who are currently undergoing treatments for cancer. We recommend that patients be cancer free. Depending on the site and severity of cancer we can may more recommendations.

Will my DNA be altered if I receive a human cell and tissue allograft?
In certain cases of bone marrow transplants, a patient’s DNA can be altered or shared with the donor. For the intent and purpose of our product, your DNA will most likely not be altered. Most procedures utilizing human cell and tissue products in regenerative medicine will typically be removed by normal body processes within 3-14 days, and in some cases up to 120 days (4-months).

Is stem cell therapy safe?

It’s difficult to find information on stem cells being harmful in people. A better question is how do stem cells know what to become in the body once injected?

If you’re injecting stem cells into an encapsulated joint like the knee the stem cells stay in that joint. Stem cells have the ability to repair, rebuild and rejuvenate tissues in the body. You already have millions of stem cells inside of your body. As we age those cells get sluggish and just aren’t as robust as “new” stem cells.

When disease or injury occurs, stem cells respond to specific signals and set out to facilitate the healing process by differentiating into specialized cells. These specialized cells then release healing growth factors in response to the distress cell signal in an injured or pathologic area of the body required for the body’s repair. The body handles this process of differentiation into the proper tissue by gene expression.

If you’ve never had a genetics course in college that’s okay. Here is some basic terminology.

Gene expression is the cellular process of creating a protein, instructed by the sequence of DNA contained within a gene. This process begins with a signal, initiating transcription of a gene. The product of transcription, mRNA, travels out of the nucleus. It interacts with specific protein machinery to transcribe the mRNA sequence into amino acid chains that fold into proteins.

Cell fate decision is the product of differential gene expression, a cell fate decision describes how exposure of stem cells to different external or internal environments can activate transcription/translation of different genes or sets of genes, producing multiple specific end-stage results.

The parent stem cell will become a self-renewed cell or a daughter cell which will differentiate into the tissue the body needs. See the diagram below.

These stem cells will replicate repeatedly. So over the course of many months millions of new cells may be created.

Because humans are 99.9% the same, the DNA framework of an undifferentiated cell is basically the same as your own. When introducing a homologous (from an another person) biologic such as a stem cell, you might think the chance of rejection would be high, however, this isn’t the case when discussing UMSC’s (umbilical mesenchymal stem cells) from donated umbilical cord martix. In an NCBI study it states, “in order for UMSC’s to survive host rejection, they either actively modulate the inflammatory response or they present cell surface components that enable them to remain invisible to the host immune system.” See study no. 1 below pertaining to the eye. These UMSC’s seem to do this very well.

Some common injuries and conditions we use stem cell therapy for in the office include:

  • arthritis
  • pain
  • meniscus tear
  • ligament tear,
  • post-surgical
  • tendinitis
  • muscular tear
  1. Donor rejection?: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4156039/

 

Knee Pain Exercises (2019)

Here is a list of the exercises I like for knee pain. Some are for beginners and some are a little more advanced. These specific exercises help to strengthen the muscles surrounding the knee.

Home Strengthening Exercises for Knee Pain

7 Best Home Stretches for Knee Pain

  1. Lunging Hip Flexor Stretch

If the hips become tight, your body will compensate and overwork the quads, which puts pressure on the knees. This stretch will open up the hips.

  • Kneel on one knee. Place the opposite foot flat in front of you, front thigh parallel to the floor.
  • Lean forward, stretching your hip toward the floor.
  • Tighten your butt; this will allow you to stretch your hip flexor even more.
  • Reach up with the arm on the same side as the knee on the floor. This will help deepen the stretch.
  • Switch sides and repeat.

  2. Figure Four Stretch

Tight glutes can also cause the quads to take too much impact, consequently putting more pressure on the knees. It can also cause back pain and pain down the leg. Avoiding tightness in the glutes will help them activate, taking the brunt of the work off your other smaller muscles down the chain.

  • Lie on your back.
  • Cross your left foot over your right quad, and bend your right knee.
  • Hold the back of your right leg and gently pull it toward your chest.
  • When you feel a comfortable stretch, hold there.
  • Switch sides and repeat.
  •  

3. Standing Hamstring Stretch

The hamstrings help support the hips and knees. It’s common that a knee injury is caused by a hamstring strain, so it’s very important that the hamstrings are staying loose and mobile to help prevent strains.

  • Stand on your right foot with your left foot in front of you, heel on the floor, toes up.
  • Hinge forward at your hips and bend your right knee as you sit back a bit.
  • As you bend your right leg, keep your left leg completely straight with your weight on the edge of your heel.
  • You should feel this stretch in the hamstring of the straightened leg.
  • Switch sides and repeat.

4. Calf Stretch

Tight calves will put pressure on the back of your knee. This can also put pressure on your feet and contribute to injuries like plantar fasciitis.

  • Stand in front of a wall with one leg straight behind you and the other in front of you, slightly bent.
  • Place your hands on the wall and push against it.
  • Keep your back leg straight, heel planted on the floor.
  • You should feel this in the calf of your back leg.
  • Switch sides and repeat.

5. Quad Stretch

The tighter the quad is, the more pressure there’s going to be on your patella, which is the kneecap. Tight quads can cause pain that feels like it’s coming from behind the kneecap.

  • Lie on one side.
  • Keep the bottom leg straight and bend the top knee so your foot is by your butt.
  • Hold the top foot with your hand, pulling it toward your butt.
  • You should feel this stretch in your quad.
  • Keep your hips stable so you’re not rocking back as you pull.
  • Switch sides and repeat.

6. Kneeling Quad Stretch

This stretch will also help loosen up the quads and take tension off the knees and hips:

  • Kneel on one knee with the opposite foot flat in front of you.
  • Grab your back foot and pull it in toward your butt.
  • Switch sides and repeat.

7. Side Lunge

This stretch works the adductors, the muscles on the inside of your thighs that help stabilize your hips. Tight adductors can cause instability in your hips and pelvis, and ultimately your knees.

  • Lunge out to one side, bending the knee and keeping the opposite leg straight.
  • Try to keep the foot of your straight leg on the floor as much as as you can.
  • Place your fingertips on the floor in front of you to balance if you need it.
  • You should feel this stretch in your hips and inner thighs.
  • Switch sides and repeat.